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Table 5 Odds of readmission in AIS according to demographic, clinical, and care setting characteristics

From: Association between medication-related adverse events and non-elective readmission in acute ischemic stroke

Characteristic

Any Readmission

p valuea

AORb(95% CI)

AIS Readmission

p valuea

AORb(95% CI)

Non-AIS Readmission

p valuea

AORb(95% CI)

Yes n (%) n = 47,170

No n (%)n = 392,512

Yes n (%)n = 6205

No n (%)n = 433,477

Yes n (%)n = 40,965

No n (%)n = 398,717

Age

 <  40

1311 (2.8)

11,567 (2.9)

<.001

1.12 (1.00–1.26)*

135 (2.2)

12,743 (2.9)

<.001

0.76 (0.55–1.04)

1176 (2.9)

11,702 (2.9)

<.001

1.20 (1.06–1.36)**

 40–49

2379 (5.0)

22,793 (5.8)

 

Reference

365 (5.9)

24,807 (5.7)

 

Reference

2014 (4.9)

23,158 (5.8)

 

Reference

 50–59

6212 (13.2)

58,151 (14.8)

 

0.97 (0.88–1.05)

929 (15.0)

63,434 (14.6)

 

1.01 (0.83–1.21)

5283 (12.9)

59,080 (14.8)

 

0.96 (0.87–1.05)

 60–69

9649 (20.5)

85,487 (21.8)

 

0.93 (0.85–1.01)

1431 (23.1)

93,705(21.6)

 

1.08 (0.90–1.30)

8218 (20.1)

86,918 (21.8)

 

0.90 (0.83–0.99)*

 70–79

11,992 (25.4)

91,829 (23.4)

 

0.97 (0.88–1.06)

1590 (25.6)

102,231 (23.6)

 

1.12 (0.91–1.37)

10,402 (25.4)

93,419 (23.4)

 

0.95 (0.86–1.05)

 80–89

11,861 (25.1)

90,080 (22.9)

 

0.93 (0.85–1.02)

1389 (22.4)

100,551 (23.2)

 

0.99 (0.81–1.22)

10,472 (25.6)

91,469 (22.9)

 

0.93 (0.84–1.02)

 90+

3766 (8.0)

32,605 (8.3)

 

0.82 (0.74–0.91)***

366 (5.9)

36,005(8.3)

 

0.72 (0.56–0.93)*

3400 (8.3)

32,971 (8.3)

 

0.84 (0.75–0.94)**

Sex

 Female

24,509 (52.0)

201,061 (51.2)

0.087

Reference

3024 (48.7)

222,546 (51.3)

0.013

Reference

21,485 (52.4)

204,085 (51.2)

0.005

Reference

 Male

22,661 (48.0)

191,450 (48.8)

 

1.03 (1.00–1.07)

3181 (51.3)

210,930 (48.7)

 

1.07 (0.99–1.17)

19,480 (47.6)

194,631 (48.8)

 

1.02 (0.99–1.06)

Primary payerc

 Private insurance

5834 (12.4)

70,149 (17.9)

<.001

Reference

1002 (16.1)

74,981 (17.3)

0.159

Reference

4832 (11.8)

71,151 (17.8)

<.001

Reference

 Medicare

34,216 (72.5)

261,439 (66.6)

 

1.33 (1.26–1.40)***

4160 (67.0)

291,495 (67.2)

 

1.02 (0.90–1.16)

30,057 (73.4)

265,598 (66.6)

 

1.39 (1.30–1.47)***

 Medicaid

4794 (10.2)

34,297 (8.7)

 

1.41 (1.32–1.51)***

636 (10.2)

38,455 (8.9)

 

1.20 (1.02–1.42)*

4158 (10.2)

34,933 (8.8)

 

1.44 (1.34–1.55)***

 Self-pay

1264 (2.7)

15,040 (3.8)

 

1.04 (0.93–1.16)

231 (3.7)

16,072 (3.7)

 

1.05 (0.81–1.37)

1033 (2.5)

15,270 (3.8)

 

1.03 (0.92–1.16)

 No charge

169 (0.4)

2139 (0.5)

 

1.01 (0.72–1.41)

42 (0.7)

2266 (0.5)

 

1.38 (0.85–2.25)

127 (0.3)

2181 (0.5)

 

0.92 (0.64–1.34)

Median household income

 $66,000+

9260 (19.6)

79,543 (20.3)

<.001

Reference

1312 (21.1)

87,492 (20.2)

0.014

Reference

7948 (19.4)

80,855 (20.3)

<.001

Reference

 $51,000 - $65,999

10,175 (21.6)

89,756 (22.9)

 

0.97 (0.92–1.02)

1327 (21.4)

98,605 (22.7)

 

0.90 (0.79–1.03)

8848 (21.6)

91,083 (22.8)

 

0.99 (0.94–1.04)

 $40,000 - $50,999

12,546 (26.6)

105,950 (27.0)

 

1.01 (0.96–1.06)

1544 (24.9)

116,952 (27.0)

 

0.88 (0.78–1.01)

11,002 (26.9)

107,493 (27.0)

 

1.04 (0.98–1.09)

 $1 - $39,999

14,620 (31.0)

112,048 (28.5)

 

1.08 (1.03–1.14)**

1952 (31.5)

124,717 (28.8)

 

1.03 (0.91–1.17)

12,668 (30.9)

114,000 (28.6)

 

1.09 (1.03–1.15)**

 Missing

569 (1.2)

5214 (1.3)

 

n/a

71 (1.1)

5712 (1.3)

 

n/a

498 (1.2)

5285 (1.3)

 

n/a

Length of stay

 0–7 days

27,070 (57.4)

279,716 (71.3)

<.001

Reference

4557 (73.4)

302,229 (69.7)

<.001

Reference

22,513 (55.0)

284,273 (71.3)

<.001

Reference

 >  7 days

20,100 (42.6)

112,796 (28.7)

 

1.38 (1.33–1.43)***

1648 (26.6)

131,248 (30.3)

 

0.75 (0.68–0.83)***

18,452 (45.0)

114,444 (28.7)

 

1.50 (1.44–1.55)***

Discharge disposition

 Routine

13,069 (27.7)

161,864 (41.2)

<.001

Reference

2265 (36.5)

172,667 (39.8)

<.001

Reference

10,803 (26.4)

164,129 (41.2)

<.001

Reference

 Transfer: short-term hospital

1306 (2.8)

7245 (1.8)

 

1.91 (1.70–2.14)***

327 (5.3)

8224 (1.9)

 

3.08 (2.44–3.90)***

979 (2.4)

7571 (1.9)

 

1.63 (1.44–1.84)***

 Transfer: other type of facility

22,491 (47.7)

142,394 (36.3)

 

1.52 (1.45–1.59)***

2168 (34.9)

162,716 (37.5)

 

1.06 (0.95–1.19)

20,322 (49.6)

144,562 (36.3)

 

1.59 (1.51–1.67)***

 Home health care

9693 (20.5)

77,296 (19.7)

 

1.26 (1.20–1.32)***

1298 (20.9)

85,691 (19.8)

 

1.19 (1.07–1.33)**

8395 (20.5)

78,594 (19.7)

 

1.27 (1.20–1.34)***

 Against medical advice

595 (1.3)

2936 (0.7)

 

2.41 (2.08–2.79)***

##

##

 

3.12 (2.29–4.23)***

450 (1.1)

3081 (0.8)

 

2.13 (1.83–2.47)***

 Discharged alive, destination unknown

16 (0.0)

777 (0.2)

 

0.20 (0.11–0.38)***

##

##

 

0.16 (0.02–1.08)

15 (0.0)

779 (0.2)

 

0.21 (0.11–0.42)***

Comorbidities

 0–2

7125 (15.1)

103,632 (26.4)

<.001

Reference

1364 (22.0)

109,392 (25.2)

0.001

Reference

5761 (14.1)

104,995 (26.3)

<.001

Reference

 3–4

16,020 (34.0)

150,414 (38.3)

 

1.36 (1.30–1.43)***

2400 (38.7)

164,034 (37.8)

 

1.20 (1.07–1.34)**

13,620 (33.2)

152,814 (38.3)

 

1.40 (1.32–1.47)***

 5–6

14,413 (30.6)

92,786 (23.6)

 

1.78 (1.68–1.87)***

1629 (26.2)

105,571 (24.4)

 

1.31 (1.16–1.47)***

12,784 (31.2)

94,415 (23.7)

 

1.86 (1.75–1.97)***

 7+

9612 (20.4)

45,680 (11.6)

 

2.20 (2.08–2.34)***

812 (13.1)

54,479 (12.6)

 

1.34 (1.15–1.55)***

8800 (21.5)

46,492 (11.7)

 

2.34 (2.19–2.49)***

Bed size of hospital

 Small

6334 (13.4)

58,615 (14.9)

<.001

Reference

920 (14.8)

64,028 (14.8)

0.533

Reference

5414 (13.2)

59,535 (14.9)

<.001

Reference

 Medium

12,747 (27.0)

107,616 (27.4)

 

1.04 (0.98–1.11)

1762 (28.4)

118,601 (27.4)

 

1.02 (0.88–1.17)

10,985 (26.8)

109,379 (27.4)

 

1.05 (0.97–1.12)

 Large

28,089 (59.5)

226,281 (57.6)

 

1.08 (1.02–1.15)*

3523 (56.8)

250,847 (57.9)

 

1.00 (0.88–1.13)

24,566 (60.0)

229,803 (57.6)

 

1.10 (1.02–1.18)*

Control/ownership of hospital

 Government, non-federal (public)

5348 (11.3)

48,360 (12.3)

<.001

Reference

732 (11.8)

52,976 (12.2)

0.081

Reference

4616 (11.3)

49,093 (12.3)

<.001

Reference

 Private, not-for-profit (voluntary)

34,592 (73.3)

291,432 (74.2)

 

1.04 (0.97–1.11)

4529 (73.0)

321,495 (74.2)

 

1.00 (0.86–1.16)

30,063 (73.4)

295,961 (74.2)

 

1.04 (0.97–1.12)

 Private, investor-owned (proprietary)

7229 (15.3)

52,720 (13.4)

 

1.20 (1.12–1.29)***

944 (15.2)

59,006 (13.6)

 

1.09 (0.91–1.30)

6286 (15.3)

53,664 (13.5)

 

1.21 (1.13–1.30)***

Teaching status of hospital

 Metropolitan teaching

30,821 (65.3)

247,949 (63.2)

<.001

Reference

3856 (62.1)

274,914 (63.4)

0.161

Reference

26,965 (65.8)

251,806 (63.2)

<.001

Reference

 Metropolitan non-teaching

12,662 (26.8)

105,886 (27.0)

 

0.97 (0.93–1.01)

1786 (28.8)

116,762 (26.9)

 

1.08 (0.97–1.19)

10,876 (26.5)

107,671 (27.0)

 

0.95 (0.91–1.00)*

 Non-metropolitan

3687 (7.8)

38,677 (9.9)

 

0.79 (0.73–0.85)***

563 (9.1)

41,801 (9.6)

 

0.92 (0.77–1.11)

3124 (7.6)

39,240 (9.8)

 

0.77 (0.71–0.84)***

  1. ##Data suppressed - 10 or fewer observations in some cells
  2. Abbreviations: AIS Acute ischemic stroke, AOR Adjusted odds ratio, CI Confidence interval
  3. ***p < 0.001; **p < 0.01; *p < 0.05
  4. aChi-square test
  5. bAdjusted for all factors listed in table
  6. cSome categories excluded due to small sample sizes