Fig. 5From: Effect of interferon beta-1a subcutaneously three times weekly on clinical and radiological measures and no evidence of disease activity status in patients with relapsing–remitting multiple sclerosis at year 1Proportion of patients with no evidence of clinical disease activity. Based on (a) absence of all protocol-defined relapses, (b) absence of Scripps-assessed moderate and/or severe relapses, or (c) absence of severe relapses, at 1 year. Based on a logistic model adjusting for age (< 40 vs. ≥40 years), sex, baseline EDSS (≤3.5 vs. > 3.5), number of relapses in 2 years prior to screening, and time since MS onset. Values within parentheses are 95% CI values. aDefined as no relapses and no 3-month confirmed disability progression (1-point increase in EDSS score if the baseline EDSS score was < 6.0 or 0.5-point increase if the baseline EDSS score was ≥6.0). (EDSS score could be > 5 if scores increase between screening and baseline.) bDefined as no relapses and no 3-month confirmed disability progression (1-point increase in EDSS score if the baseline EDSS score was < 6.0 or 0.5-point increase if the baseline EDSS score was ≥6.0). (EDSS score could be > 5 if scores increase between screening and baseline.) Relapses are defined as Scripps-assessed moderate and/or severe. cDefined as no relapses and no 3-month confirmed disability progression (1-point increase in EDSS score if the baseline EDSS score was < 6.0 or 0.5-point increase if the baseline EDSS score was ≥6.0). (EDSS score could be > 5 if scores increase between screening and baseline.) Relapses are defined as Scripps-assessed severe. EDSS: Expanded Disability Status Scale; IFN β-1a: interferon beta-1a; OR: odds ratio; SC: subcutaneously; tiw: three times weeklyBack to article page