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Fig. 2 | BMC Neurology

Fig. 2

From: Targeting the Notch1 oncogene by miR-139-5p inhibits glioma metastasis and epithelial-mesenchymal transition (EMT)

Fig. 2

Notch1 was upregulated in glioma and cell lines and associated with tumour grade. (a) Notch1 expression was analyzed in GBM tissues and non-tumor brain tissues from the Bredel Brain and Sun brain data sets. (b) Notch1 mRNA expression was analyzed in GBM tissues from the TCGA data sets. (c) Representative images of Notch1 expression in different grades of glioma tissues and normal brain tissues were shown using immunohistochemical assay (× 100 magnification). (d) Western blotting assay showed that T98G, U251, LN229 and U87 glioma cells expressed higher levels of Notch1 than the Olig cell line

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BMC Neurology

ISSN: 1471-2377

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