Table 2 Post-translational modifications (PTMs) of 18 isoforms of cerebrospinal fluid alpha-1-antitrypsin
SPOT NUMBER | Mw (kDa) | pI | Unique peptides | Peptides position START-END | PTM |
|---|---|---|---|---|---|
1605 | 153.0 | 5.50 | 18 | 35–418 | N-glycosylation |
1606 | 153.0 | 5.52 | 18 | 35–418 | N-glycosylation |
2601 | 153.0 | 5.54 | 18 | 35–418 | N-glycosylation |
1310 | 70.9 | 5.25 | 14 | 35–418 | – |
1308 | 69.5 | 5.35 | 20 | 35–418 | – |
2311 | 69.5 | 5.39 | 25 | 35–418 | – |
2310 | 68.2 | 5.44 | 25 | 35–418 | – |
2308 | 68.2 | 5.50 | 31 | 35–418 | – |
216 | 36.7 | 4.78 | 6 | 180–411 | N-terminal truncation |
215 | 35.4 | 4.80 | 16 | 126–418 | N-terminal truncation |
214 | 33.4 | 4.90 | 6 | 35–241 | C-terminal truncation |
111 | 38.9 | 5.10 | 10 | 126–418 | N-terminal truncation |
110 | 37.4 | 5.15 | 16 | 154–418 | N-terminal truncation |
5106 | 19.4 | 6.50 | 7 | 299–418 | N-terminal truncation |
1505 | 57.6 | 5.3 | 12 | 35–418 | N-glycosylation |
2504 | 60.9 | 5.5 | 12 | 35–418 | N-glycosylation |
2508 | 68.3 | 5.5 | 12 | 35–418 | N-glycosylation |
2512 | 68.2 | 5.4 | 12 | 35–418 | N-glycosylation |