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Table 1 Baseline data for patients and s-IGF-I in each of the quintiles of changing s-IGF-I (ΔIGF-I-q1–5)

From: Altered levels of circulating insulin-like growth factor I (IGF-I) following ischemic stroke are associated with outcome - a prospective observational study

Parameter

Unit

Value

n

 

354

Age at index ischemic stroke

Years (SD)

55.4 (11)

Sex

Missing (N)

229/125

Male/female (fraction)

0.65

Diabetes

Yes (N/fraction)

67 (0.19)

Missing (N)

0

Hypertension

Yes (N/fraction)

188 (0.53)

Missing (N)

0

Current smoking

Yes (N/fraction)

136 (0.38)

Missing (N)

0

LDL level (ng/nL)

Mean (SD)

3.3 (1.0)

Missing (N)

27

P-glucose (acute)

Mean (SD)

6.5 (2.64)

Missing (N)

8

P-glucose (3 m)

Mean (SD)

6.03 (2.29)

Missing (N)

8

Stroke severity (NIHSS)

Mean (20, 80%)

5.3 (0.7, 10.2)

Missing (N)

0

Stroke outcome (mRS) 3 m

Mean(SD)

1.85 (1.06)

Missing (N)

5

Stroke outcome (mRS) 2 yr

mRS (SD)

1.77 (1.32)

Missing (N)

2

Dead (3-24 m)

Yes (n/fraction)

9 (0.025)

Missing (N)

0

s-IGF-I (acute)

ng/mL (SD)

172.8 (62.9)

Missing (N)

0

s-IGF-I (3 m)

ng/mL (SD)

152.7 (55.7)

Missing (N)

0

ΔIGF-I (ng/mL), all data

ng/mL (SD)

20.2 (51.0)

Missing (N)

0

Quintile of ΔIGF-I:

 

ΔIGF-I (ng/mL)

s-IGF-I acute (ng/mL)

Change (%)

 

ΔIGF-I-q1 (SD)

− 48.3 (48.0)

146.5 (53.7)

incr. 33.0

 

(N)

71

71

71

 

ΔIGF-I-q2 (SD)

1.6 (5.8)

145.4 (44.6)

decr. 1.10

 

(N)

72

72

72

 

ΔIGF-I-q3 (SD)

20.8 (5.7)

152.5 (56.0)

decr 13.5

 

(N)

71

71

71

 

ΔIGF-I-q4 (SD)

42.5 (7.2)

178.9 (45.9)

decr 23.6

 

(N)

70

70

70

 

ΔIGF-I-q5 (SD)

85.9 (28.0)

240.5 (57.6)

decr 35.7

 

(N)

70

70

70

  1. Absolute ΔIGF-I (ng/mL) represents a subtraction of acute s-IGF-I by 3-month s-IGF-I. A negative numerical value represents an increase from the acute to 3-month time point, and a positive numerical value represents a decrease. Modified Rankin scale (mRS), low density lipoprotein (LDL), National Institutes of Health Stroke Scale (NIHSS). An extended version of the table with a comparison to data presented in 2011 is found in Additional file 2: Table S1