Skip to main content

Table 13 Comparison of Different Composite Scores for Predicting HT in AIS Patients

From: The hemorrhagic transformation index score: a prediction tool in middle cerebral artery ischemic stroke

Score

Predictors

Sample Size

Cerebral Vascular Territory

Predicted Outcome

IV rtPA Settings

Cucchiara [6]

Clinical

Age, NIHSS

1205

Any

Any HT

Yes

Laboratory

Glucose, platelet count

GRASPS [9]

Clinical

Age, ethnicity, NIHSS, sex, SBP

10,242

Any

SHT

Yes

Laboratory

Glucose

HAS-BLED [46]

Clinical

Age, alcohol abuse, bleeding history, drugs, SBP, stroke/TIA

3978

Any

Major Bleedinga

No

Laboratory

Liver and renal function tests, INR

HAT [5]

Clinical

Diabetes mellitus, NIHSS

400

Any

SHT

Yes

Imaging

ASPECTS

Laboratory

Glucose

HeRS [31]

Clinical

Age

345

Any

Any HT

Regardless

Imaging

Infarct volume

Laboratory

Estimated glomerular filtration rate

HTI

Clinical

NIHSS

783

MCA

Any HT

Regardless

Imaging

ASPECTS, HMCA sign

Laboratory

AF on ECG

iScore [32]

Clinical

AF, age, cancer, chronic heart failure, NIHSS, preadmission disability, renal dialysis, sex, stroke subtype

1696

Any

Any HT

Yes

Laboratory

Glucose

SEDAN [8]

Clinical

Age, NIHSS

1802

Any

SHT

Yes

Imaging

ASPECTS, HMCA sign

Laboratory

Glucose

SITS-SICH [7]

Clinical

Age, antiplatelet medication, hypertension, NIHSS, stroke onset to treatment time, SBP, weight

31,627

Any

SHT

Yes

Laboratory

Glucose

SPAN-100 [33]

Clinical

Age, NIHSS

624

Any

Any HT

Regardless

  1. Note: a1-year risk for major bleeding (intracranial, hospitalization, hemoglobin decrease > 2 g/L, and/or transfusion) in a cohort of real-world patients with AF