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Table 4 Deep gray matter data: between group and between field strength comparisons

From: Automated segmentation of cerebral deep gray matter from MRI scans: effect of field strength on sensitivity and reliability

  

MS group (n = 14)

NC group (n = 15)

pa, b MS vs NC

 

DGM structure

1.5T

3T

p (MS) 1.5T vs. 3T

1.5T

3T

P (NC) 1.5T vs 3T

1.5T

3T

Volumes (ml)

Thalamus

14.4 (1.4)

11.7–16.3

14.7 (1.5)

12.6–16.7

0.003

15.2 (1.0)

12.9–16.3

16.0 (1.0)

13.6–17.1

<0.0001

0.05

0.02

Caudate

6.2 (0.9)

4.9–7.8

6.5 (0.9)

5.0–8.2

0.0001

6.9 (0.8)

5.2–8.6

7.3 (0.9)

5.6–9.4

<0.0001

0.09

0.10

Putamen

8.7 (0.7)

7.4–9.7

9.0 (0.7)

7.6–10.1

<0.0001

9.6 (0.8)

8.6–11.7

10.1 (0.9)

9.1–12.6

<0.0001

0.03

0.02

Globus pallidus

2.9 (0.3)

2.4–3.4

3.1 (0.4)

2.6–3.9

0.0004

3.3 (0.3)

2.9–3.7

3.6 (0.3)

3.2–4.0

<0.0001

0.0006

0.0004

Total DGM

32.2 (2.8)

26.4–37.1

33.4 (3.0)

28.1–38.6

<0.0001

35.0 (2.6)

30.9–40.2

37.0 (2.6)

32.8–42.8

<0.0001

0.02

0.01

Fractions

Thalamus

0.011 (0.0011)

0.0087–0.013

0.012 (0.00097)

0.0096–0.013

0.12

0.0116 (0.00058)

0.010–0.013

0.012 (0.00063)

0.011–0.013

0.0004

0.31

0.23

Caudate

0.0049 (0.00057)

0.0037–0.0056

0.0051 (0.00058)

0.0040–0.0059

0.007

0.0053 (0.00046)

0.0040–0.0060

0.0055 (0.00053)

0.0043–0.0066

0.0004

0.20

0.30

Putamen

0.0068 (0.00055)

0.0055–0.0078

0.0071 (0.00057)

0.0057–0.0080

0.0001

0.0074 (0.00051)

0.0065–0.0081

0.0077 (0.00053)

0.0068–0.0088

<0.0001

0.20

0.20

Globus pallidus

0.0023 (0.00021)

0.0018–0.0026

0.0024 (0.00024)

0.0020–0.0028

0.0002

0.0025 (0.00017)

0.0023–0.0028

0.0028 (0.00013)

0.0025–0.0030

<0.0001

0.009

0.003

Total DGM

0.0252 (0.0020)

0.0197–0.0282

0.0261 (0.0019)

0.0213–0.0280

0.002

0.0268 (0.0013)

0.0236–0.0290

0.0282 (0.0013)

0.0256–0.0299

<0.0001

0.11

0.07

  1. Key: Data are mean (standard deviation) on first line; range on second line; Percent differences between 1.5T and 3T are shown in Table 5; DGM = cerebral subcortical deep gray matter; MS multiple sclerosis, NC normal controls; aage adjusted; bthe differentiation (sensitivity) between MS and NC was similar for 1.5 versus 3T (all p > 0.05)
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BMC Neurology

ISSN: 1471-2377

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