From: Clinical and electrophysiological features of post-traumatic Guillain-Barré syndrome
Characteristic | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | Case 6 |
---|---|---|---|---|---|---|
Age (y)/Sex | 29/F | 48/F | 29/F | 57/M | 53/F | 39/M |
Antecedent events | Abortion | mild Traumatic brain injury | Cesarean section | Chest trauma | Endoscopic endonasal resection of Rathke cyst | Femoral fracture |
Time between trauma and symptom onset (days) | 14 | 10 | 8 | 10 | 12 | 12 |
Time between treatment initiation and symptom onset (days) | 6 | 5 | 6 | 11 | 9 | 5 |
Time to nadir (days) | 9 | 7 | 10 | 5 | 12 | 7 |
Time to discharge (days) | 33 | 43 | 21 | 56 | 38 | 22 |
Symptoms at nadir | ||||||
Motor function | Weakness on both limbs (G2/5) | Weakness on both limbs (G2/5) | Weakness on both limbs (G3/5) | Weakness on both limbs (G1/5) | Weakness on both limbs (G2/5) | Weakness on both limbs (G3/5) |
Deep tendon reflexes | Absent (G —) | Absent (G —) | Decreased (G1+) | Absent (G —) | Absent (G —) | Decreased (G1+) |
Muscular atrophy at nadir | + | + | + | + | + | + |
Cranial nerve function | III, IV, VI, VII | II, III, IV, VI | III, IV, VI | V, IX, X | − | III, IV |
Respiratory muscle involvement | − | + | − | + | − | − |
Objective sensory function | Normal | Normal | Abnormal | Normal | Normal | Abormal |
Serum anti-ganglioside antibody | GQ1b | GM1 | GM1,GD1b | − | Missing | GM1,GD1b |
Protein (g/L)/AD in CSF | 0.98/yes | 0.64/yes | 1.10/yes | 0.92/yes | 0.54/yes | 0.72/yes |
Treatment | IVIG | IVIG; MV | IVIG | IVIG; HC; MV | IVIG | IVIG |