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Table 2 Treatment exposure (FAS)

From: Effectiveness of the capsaicin 8% patch in the management of peripheral neuropathic pain in European clinical practice: the ASCEND study

 

PHN

(n = 89)

HIV-AN

(n = 5)

NBP

(n = 50)

CRNP

(n = 22)

PONP

(n = 198)

Other

(n = 56)

Overall

(n = 420)

Patients treated at each application, n (%)

 First treatment

89 (21.2)

5 (1.2)

50 (11.9)

22 (5.2)

198 (47.1)

56 (13.3)

420 (100)

 Second treatment

40 (9.5)

2 (0.5)

15 (3.6)

8 (1.9)

97 (23.1)

19 (4.5)

181 (43.1)

 Third treatment

16 (3.8)

–

4 (1.0)

4 (1.0)

38 (9.0)

8 (1.9)

70 (16.7)

Mean size of treatment area, cm2 (SD)

 First treatment

298.6 (168.1)

380.0 (138.6)

297.7 (196.9)

519.5 (404.9)

271.5 (209.7)

362.0 (263.9)

306.4 (228.2)

 Second treatment

286.8 (169.3)

210.0 (99.0)

291.3 (160.6)

566.6 (387.9)

278.6 (206.4)

391.5 (300.5)

306.4 (225.0)

 Third treatment

270.0 (190.6)

–

357.5 (230.7)

467.5 (113.5)

229.7 (211.8)

487.4 (412.4)

294.8 (248.8)

Mean number of patches (SD)

 First treatment

1.4 (0.6)

1.4 (0.6)

1.3 (0.6)

2.1 (1.3)

1.4 (0.7)

1.6 (0.8)

1.5 (0.7)

 Second treatment

1.4 (0.6)

1.0 (0.0)

1.4 (0.6)

2.3 (1.2)

1.5 (0.7)

1.7 (0.9)

1.5 (0.7)

 Third treatment

1.4 (0.7)

–

1.8 (1.0)

2.0 (0.0)

1.4 (0.8)

2.0 (1.3)

1.6 (0.8)

Patients completing ≥90% of recommended treatment durationa, n (%)

 First treatment

84 (94.4)

5 (100)

47 (94.0)

19 (86.4)

184 (93.9)

49 (87.5)

388 (92.8)

 Second treatment

37 (94.9)

2 (100)

12 (85.7)

7 (87.5)

81 (94.2)

18 (100)

157 (94.0)

 Third treatment

16 (100)

–

4 (100)

4 (100)

33 (100)

7 (87.5)

63 (98.4)

  1. aRecommended treatment duration times were 30 min for foot and 60 min for other anatomical locations. For patients treated on the foot, the treatment time corresponding to the percentage duration was 27–33 min for ≥90% to <110% and >33 min for ≥110%. For patients treated on other locations, the treatment time corresponding to the percentage duration was 54–66 min for ≥90% to <110% and >66 min for ≥110%. CRNP, cancer-related neuropathic pain; FAS, full analysis set; HIV-AN, HIV associated neuropathy; NPRS, numeric pain rating scale; PHN, postherpetic neuralgia; NBP, neuropathic back pain; Other, other non-diabetic PNP; PONP, post-operative and post-traumatic neuropathic pain; SD, standard deviation