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Table 1 Baseline disease characteristics (Calabresi et al. [5])

From: Peginterferon beta-1a improves MRI measures and increases the proportion of patients with no evidence of disease activity in relapsing-remitting multiple sclerosis: 2-year results from the ADVANCE randomized controlled trial

Characteristic

Placebo

Peginterferon beta-1a

Every 4 weeks

Every 2 weeks

All patients, n

500

500

512

Relapses in the 12 months prior to enrolment, mean (SD)

1.6 (0.67)

1.5 (0.62)

1.6 (0.67)

Baseline EDSS score, mean (SD)

2.44 (1.18)

2.48 (1.24)

2.47 (1.26)

T2 lesions at baseline

 Patients with available data, n

497

499

511

 Mean number of lesions (SD)

50.6 (35.7)

51.4 (36.0)

48.7 (36.8)

 Patients with no T2 lesions at baseline, n (%)

0

3 (<1)

4 (<1)

Gd + lesions at baseline

 Patients with available data, n

497

498

510

 Mean number of lesions (SD)

1.6 (3.8)

1.8 (5.4)

1.2 (3.4)

 Patients with no Gd + lesions at baseline, n (%)

296 (59.6)

297 (59.6)

334 (65.5)

  1. EDSS expanded disability status scale, Gd+ gadolinium-enhancing lesions, SD standard deviation