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Table 1 Demographic and anthropometric data on all patients, MS patients and HSP/HA patients

From: Bone mineral density in patients with multiple sclerosis, hereditary ataxia or hereditary spastic paraplegia after at least 10 years of disease - a case control study

 

All

MS

HSP/HA

Number (%)

168 (100)

91 (54.4)

77 (45.6)

Women (%)

82 (48.8)

46 (50.5)

36 (46.8)

Disease phenotype (%)

 

RRMS 51 (56.0)

SPMS 34 (37.4)

PPMS 6 (6.6)

HSP 61 (79.2)

HA 12 (15.6)

HSP w/ataxia 4 (5.2)

Age (SD)

55.3 (±10.4)

52.0 (±10.3)

52.7 (±10.6)

Disease duration >20 years (%)

93 (55.4)

46 (50.5)a

47(61.0)

Years since onset (SD)

24.2 (±12.8)

21.3 (±9.0)a

27.7 (±15.4)

Disability (SD)

 No aid

84 (50.0)

49 (53.8)

35 (45.5)

 One or two sticks

65 (38.7)

31 (34.1)

34 (44.2)

 In wheel chair

19 (11.3)

11 (12.1)

8 (10.4)

EDSS

 

4.9 (median 5.0, range: 1.5-8.0)

 

Height, cm (SD)

172.7 (±8.6)

173.2 (±8.3)

172.1 (±8.9)

Weight, kg (SD)

74.3 (±16.3)

71.8 (±14.1)a

77.2 (±18.2)

BMI Kg/m2 (SD)

24.8 (±4.5)

23.9 (±4.2)a

25.8 (±4.7)

Total body fat % (SD)

32.3 (±8.5)

31.6 (±8.5)

33.0 (±8.5)

  1. Abbreviations: EDSS Expanded Disability Status Scale, RRMS relapsing remitting multiple sclerosis, SPMS secondary progressive multiple sclerosis, PPMS primary progressive multiple sclerosis, HSP hereditary spastic paraplegia, HA hereditary ataxia, BMI body mass index
  2. ap <0.05 (independent sample t-test) compared to patients with HSP/HA