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Table 2 Actual cost for 726 patients = cost for S100B + cost for all the CT taken + cost for all the patients hospitalized

From: The addition of S100B to guidelines for management of mild head injury is potentially cost saving

  S100 = 21 € CT = 130 € Hospitalization = 366 € Tot
ACTUAL COST in follow-up (cost per patient)   726 × 21 € = 15 246 € 398 × 130 € = 51 740 € 297 × 366 € = 108 702 € 175 688 € (242 €)
POTENTIAL COST given different assumptions S100B not in guidelines and assuming same use of CT and hospitalization as for cohort   0,7 x 726 x 130 € = 66 066 € 0,52 x 726 x 366 € = 138 172 € 204 238 € (281€)
Strict compliance based on guidelines for S100 + CT only 726 × 21 € = 15 246 € CT (S100B+)
497 × 130€ = 64 610 €
  79 856 € (110 €)
  1. Potential cost for 726 patients given different assumptions:
  2. -if S100B is not included in guidelines= 156 patients with S100B negative were directly dismissed, we calculated an hypothetical cost if they underwent a CT or were hospitalized
  3. -strict compliance based on guidelines= we considered that all the patients with a negative S100B were dismissed (138 patients) and took into account only the cost for S100 B positive patients