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Fig. 1 | BMC Neurology

Fig. 1

From: Improving clinical trial design for Duchenne muscular dystrophy

Fig. 1

DMD course and treatment outcomes. A DMD boy beginning treatment at age 5 (arrow) when he has already lost some motor function/muscle strength (line A) compared with normal peers (line N). Without treatment, he will continue to deteriorate, finally loosing ambulation between 7–12 years of age (black triangle – B). The red area (C) represents the outcome of a treatment able to arrest (base of the red trapezoid) or partially or completely to restore (leg of the trapezoid) lost function. The green area (D) represents the outcome of a treatment able to slow the progression of the disease with loss of autonomous ambulation after the age of 14 years

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