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Table 2 Frequencies of pathologies within aMCI (N = 34) and naMCI (N = 15) cases. All pathology groups are not mutually exclusive; there is considerable overlap with concomitant pathologies

From: Neuropathological comparisons of amnestic and nonamnestic mild cognitive impairment

  aMCI naMCI p value
Clinicopathologic diagnoses    
 PD 8 (24 %)a 7 (47 %) 0.18
 PSP 3 (9 %)a 3 (20 %) 0.35
 MND 0 1 (7 %) 0.31
 MSA 1 (3 %) 0 1.00
Other pathologies    
Met neuropath criteria for AD 18 (53 %) 8 (53 %) 1.00
 Braak NFT stage    0.22
  I 2 (6 %) 0  
  II 2 (6 %) 2 (13 %)  
  III 3 (9 %) 5 (33 %)  
  IV 23 (68 %) 8 (53 %)  
  V 3 (9 %) 0  
  VI 1 (3 %) 0  
 CERAD NP score    0.90
  None 12 (35 %) 6 (40 %)  
  Sparse 2 (6 %) 1 (7 %)  
  Moderate 8 (24 %) 2 (13 %)  
  Frequent 12 (35 %) 6 (40 %)  
Incidental LBs 5 (15 %) 0 0.31
Unified LB staging scheme    0.18
 Stage 0. no LBs 21 (62 %) 8 (53 %)  
 Stage 1. OBT only 2 (6 %) 0  
 Stage IIa. Brainstem 3 (9 %) 1 (7 %)  
 Stage IIb. Limbic 3 (9 %) 0  
 Stage III. Limbic + Brainstem 3 (9 %) 3 (20 %)  
 Stage IV. Neocortical 2 (6 %) 3 (20 %)  
  1. aOne aMCI case had both PSP and PD; there were no other overlapping clinicopathological diagnoses