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Table 5 Association between PD-ICB and polymorphisms in genotypes among cases and controls

From: DRD and GRIN2B polymorphisms and their association with the development of impulse control behaviour among Malaysian Parkinson’s disease patients

Model

Genotype

Control (%)

Case (%)

OR (95% CI)

DRD1 rs4532 (C > T)

 

Overdominant

CC-TT

35 (94.6)

32 (61.5)

1.00

TC

2 (5.4)

20 (38.5)

21.33 (1.97-230.64)**

DRD1 rs4867798 (T > C)

 

Recessive

TT-TC

29 (96.7)

32 (71.1)

1.00

CC

1 (3.3)

13 (28.9)

24.53 (1.68-357.28)**

DRD2/ANKK1 rs1800497 (C > T)

 

Log-additive

T-

-

-

3.77 (1.38-10.30) **

GRIN2B rs7301328 (G > C)

 

Recessive

GG-CG

24 (82.8)

20 (47.6)

1.00

CC

5 (17.2)

22 (52.4)

25.07 (1.30-483.41) **

  1. **,p < 0.01, which indicates a statistically significant difference.