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Table 2 Association results

From: Decision tree analysis of genetic risk for clinically heterogeneous Alzheimer’s disease

Gene

SNP

OR

STAT

P

MAF

APOE

rs429358/rs7412

4.28

4.83

1.36E-06

0.20

HFE

rs1799945

2.83

3.15

1.64E-03

0.15

PICALM

rs3851179

0.47

−3.04

2.37E-03

0.42

CR1

rs6701713

0.42

−2.65

0.01

0.19

SLC6A4

rs2020942

1.81

2.63

0.01

0.40

TPH1

rs1799913

0.64

−2.02

0.04

0.44

KIAA0319

rs4504469

0.60

−2.02

0.04

0.35

CDC42BPA

rs1320490

1.63

1.93

0.05

0.20

TMEM175

rs6599389

0.41

−1.81

0.07

0.08

SORL1

rs2070045

1.63

1.74

0.08

0.22

CNTNAP2

rs17236239

0.66

−1.61

0.11

0.16

ATP2C2

rs8053211

1.45

1.56

0.12

0.43

CD2AP

rs9349407

1.48

1.55

0.12

0.29

TPD52

rs7814569

1.79

1.53

0.13

0.09

COMT

rs4680

0.72

−1.41

0.16

0.50

C9ORF72

rs3849942

1.42

1.38

0.17

0.24

CPE

rs11186856

0.33

−1.37

0.17

0.33

SORL1

rs12285364

0.42

−1.34

0.18

0.04

RIT2

rs4130047

0.70

−1.33

0.18

0.31

MOBP

rs1768208

0.72

−1.3

0.19

0.29

  1. Top 20 association results in the Discovery cohort. Only APOE was significant after Bonferroni correction for multiple testing. OR – odds ratio; STAT – test statistic; MAF – minor allele frequency.