Table 2 Treatment Groups and animal numbers
Masseter surgery | Injection/pump solution | Sex | # of rats |
|---|---|---|---|
Experiment #1 | Â | Â | Â |
Sham surgery | No injection | male | 12 |
Unilateral ligature | No injection | male | 10 |
Bilateral ligature | No injection | male | 12 |
Sham surgery | No injection | female | 12 |
Bilateral ligature | No injection | female | 12 |
Experiment #2 | Â | Â | Â |
Sham surgery | vehicle | male | 8 |
Bilateral ligature | vehicle | male | 8 |
Sham surgery | control virus (SHZ) | male | 6 |
Bilateral ligature | control virus (SHZ) | male | 6 |
Sham surgery | enkephalin virus (SHPE) | male | 6 |
Bilateral ligature | enkephalin virus (SHPE) | male | 6 |
Sham surgery | vehicle | female | 8 |
Bilateral ligature | vehicle | female | 8 |
Sham surgery | control virus (SHZ) | female | 6 |
Bilateral ligature | control virus (SHZ) | female | 6 |
Sham surgery | enkephalin virus (SHPE) | female | 6 |
Bilateral ligature | enkephalin virus (SHPE) | female | 6 |
Experiment #3 | Â | Â | Â |
Bilateral ligature | control virus (SHZ) | male | 8 |
Bilateral ligature | enkephalin virus (SHPE) | male | 8 |
Experiment #4 | Â | Â | Â |
Bilateral ligature | enkephalin virus (SHPE)/ vehicle pump | male | 6 |
Bilateral ligature | enkephalin virus (SHPE)/ naloxone pump | male | 6 |
Bilateral ligature | enkephalin virus (SHPE)/ naloxone methiodide pump | male | 6 |