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Figure 7 | BMC Neurology

Figure 7

From: Attenuation of myogenic orofacial nociception and mechanical hypersensitivity by viral mediated enkephalin overproduction in male and female rats

Figure 7

Experiment #4. Meal duration and von Frey filament testing of ligatured male rats given opioid antagonist and a viral enkephalin expression vector. Osmotic pumps releasing vehicle, naloxone or naloxone methiodide were surgically implanted subcutaneously in rats. Rats were injected with SPHE virus 72 hours after pump implantation. A ligature was placed around the tendon of the masseter muscle 72 hours after SPHE virus injection. Meal duration (panel A) was reported for the day after and von Frey filament testing (panel B) was reported on the 4th day after ligature surgery (see Table 1). Significant differences (p < 0.05) between the groups are indicated by an asterisk. Values are the means ± SEM. See Table 2 for the number of animals per group.

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