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Table 2 Atherosclerotic marker factors associated with new vascular events at one-year follow-up

From: The ARTICO study: identification of patients at high risk of vascular recurrence after a first non-cardioembolic stroke

 

Primary end-point

 

Yes (n = 78)

No (n = 485)

p

PAD

  

<0.0001

  No (ABI >0.90)

44.2

70.7

 

  Asymptomatic (ABI ≤0.90)

37.7

21.7

 

  Symptomatic (ABI ≤0.90 or ABI >0.90)

18.2

7.6

 

ICA Stenosis >50%

29.9

18.1

0.01

Vascular disease

  

<0.0001

  Normal ABI and ICA <50%

38.2

60.9

 

  Normal ABI and ICA >50%

6.6

10.0

 

  ABI <0.9 and ICA <50%

19.7

15.5

 

  Symptomatic PAD and ICA <50%

11.8

5.1

 

  ABI <0.9 and ICA >50%

17.1

5.9

 

  Symptomatic PAD and ICA >50%

6.6

2.5

 

Atheromatous plaques

  

0.28

  None

20.0

28.4

 

  Isolated plaque

17.3

17.5

 

  Multiple plaques

62.7

54.1

 

Echogenicity of plaques

  

0.35

  Type I (uniform anechoic)

12.1

13.4

 

  Type II (mainly hypoechoic)

15.5

16.4

 

  Type III (mainly hyperechoic)

19.0

24.7

 

  Type IV (uniform iso- or hyperechoic)

51.7

39.3

 

  Type V (calcified)

1.7

6.3

 

Plaques surface

  

0.19

  Smooth and even

61.3

72.8

 

  Uneven

37.1

25.8

 

  Ulcerated

1.6

1.4

 

IMT mm (mean, SD)

0.94 (0.46)

0.91 (0.38)

0.57

Microalbuminuria

18.2

22.4

0.52

  1. All values are percentages unless otherwise stated.
  2. ABI: ankle brachial index. ICA: internal carotid stenosis (either ipsi or contralateral to index stroke). IMT: intima-media thickness. PAD: peripheral artery disease.
  3. p-value (Log-Rank test), apart from IMT (t-Student).