Skip to main content

Table 1 Demographic and clinical characteristics between NMOSD without and with autoimmune diseases, and between NMOSD with non-organ-specific and organ-specific autoimmune diseases

From: Neuromyelitis optica spectrum disorders without and with autoimmune diseases

 

NMOSD

 

NMOSD with autoimmune diseases

 

Without autoimmune diseases (n = 115)

With autoimmune diseases (n = 40)

P

Non-organ-specific (n = 22)

Organ-specific (n = 18)

P

Gender, F: M

91: 24

37: 3

0.055

22: 0

15: 3

0.165

Age, years

37.63 ± 14.33

40.71 ± 13.80

0.240

40.90 ± 14.86

40.47 ± 12.80

0.924

Age at onset, years

34.20 ± 13.70

37.37 ± 13.50

0.207

36.91 ± 14.63

37.94 ± 12.37

0.814

Disease duration, years

1.83 (0.08, 30.00)

1.33 (0.08, 31.08)

0.219

1.25 (0.08, 31.08)

2.67 (0.08, 7.00)

0.414

Annualized relapse rate

0.66 (0, 12.00)

0.89 (0, 6.00)

0.183

0.80 (0, 3.43)

0.95 (0, 6.00)

0.784

EDSS at last visit

2.0 (0, 23.0)

2.5 (0, 10.0)

0.067

2.5 (1.0, 8.5)

3.0 (0, 10.0)

0.529

Clinical features, n (%)

      

Headache

18 (15.7%)

8 (20.0%)

0.526

3 (13.6%)

5 (27.8%)

0.475

Nystagmus

6 (5.2%)

4 (10.0%)

0.289

2 (9.1%)

2 (11.1%)

0.832

IHN

26 (22.6%)

12 (30.0%)

0.349

4 (18.2%)

8 (44.4%)

0.071

Bulbar paralysis

9 (7.8%)

2 (5.0%)

0.549

1 (4.5%)

1 (5.6%)

1.000

Bowel or bladder dysfunction

49 (42.6%)

18 (45.0%)

0.793

7 (31.8%)

11 (61.1%)

0.064

Visual impairment

98 (85.2%)

33 (82.5%)

0.682

18 (81.8%)

15 (83.3%)

0.900

Motor deficit

68 (59.1%)

21 (52.5%)

0.465

8 (36.4%)

13 (72.2%)

0.024*

Sensory deficit

83 (72.2%)

25 (62.5%)

0.252

14 (63.6%)

11 (61.1%)

0.870

Neuropathic pain

29 (25.4%)

13 (32.5%)

0.388

6 (27.3%)

7 (38.9%)

0.435

  1. Abbreviations: EDSS Expanded Disability Status Scale, F: M female: male, IHN intractable hiccup and nausea, NMOSD neuromyelitis optica spectrum disorders.
  2. *p < 0.05.