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Table 2 Risk factors for asymptomatic ICAD

From: Clinical, lifestyle, socioeconomic determinants and rate of asymptomatic intracranial atherosclerosis in stroke free Pakistanis

RISK FACTORS

Frequency of patients with ICAD (%)

Frequency of patients without ICAD (%)

Unadjusted PR (CIs)

Adjusted PR (CIs)

P-value (<0.05 sig.)

Socioeconomic status

     

Low

24 (34.8%)

42 (32.1%)

1

1

0.05

Middle

16 (23.2%)

51 (38.9%)

0.66 (0.35-1.24)

0.67 (0.33-1.35)

.07

High

29 (42%)

38 (29%)

1.21 (0.70-2.08)

2.26 (1.99-5.62)

0.03

Clinical risk factors

     

Diabetes

4 (5.8%)

14 (10.7%)

0.62 (0.23-1.70)

0.58 (0.2-1.67)

0.27

Hypertension

17 (24.6%)

36 (27.5%)

0.97 (0.84-1.12)

0.98 (0.89-1.08)

0.76

Dyslipidemia

7 (10.3%)

3 (2.2%)

1.16 (0.37-3.70)

1.88 (1.25-2.21)

0.04

CVD

2 (2.9%)

1 (.8%)

0.51 (0.13-2.09)

0.30 (0.06-1.43)

0.13

A.Fib

1 (1.4%)

2 (1.5%)

1.04 (0.15-7.49)

1.44 (0.17-3.39)

0.73

Lifestyle factors

     

Current smoking

5 (7.2%)

11 (8.4%)

1.12 (0.45-2.78)

1.73 (0.24-2.27)

0.59

Past smoking

3 (4.3%)

10 (7.6%)

1.54 (0.48-4.89)

2.19 (0.51-3.81)

0.30

Smokeless tobacco

19 (27.9%)

5 (3.8%)

1.76 (0.71-4.36)

3.27 (1.07-6.05)

0.02

BMI categories

     

Normal

11 (16%)

15 (11.5%)

1

1

0.67

Underweight

20 (29%)

39 (29.8%)

1.30 (0.62-2.71)

1.73 (0.77-3.88)

0.21

Pre-over weight

10 (14.5%)

20 (15.3%)

0.98 (0.46-2.10)

0.92 (0.45-1.84)

0.64

Over-weight

14 (20.3%)

34 (26%)

0.86 (0.44-1.70)

1.18 (0.54-2.60)

0.75

Obese

13 (18.8%)

23 (17.6%)

1.07 (0.53-2.14)

1.13 (0.53-2.38)

0.70

Central obesity

     

Waist

19 (27.5%)

30 (23%)

1.20 (0.70-2.03)

1.14 (0.64-2.03)

0.65

Circumference > 80 cms

     

Physical activity

     

Low

56 (81.2%)

106 (81%)

1

1

0.84

Moderate

3 (4.3%)

6 (4.6%)

0.96 (0.30-3.06)

1.04 (0.32-3.41)

0.09

High

10 (14.5%)

19 (14.5%)

0.99 (0.51-1.94)

1.25 (0.59-2.65)

0.54

Western diet

     

Quintile 1

6 (8.7%)

31 (23.7%)

1

1

0.15

Quintile 2

16 (23.2%)

23 (17.6%)

2.46 (0.96-6.29)

2.24 (0.79-6.39)

0.10

Quintile 3

18 (26%)

21 (16%)

2.77 (1.10-6.98)

2.58 (0.95-2.61)

0.14

Quintile 4

13 (18.8%)

26 (19.8%)

2.01 (0.76-5.26)

2.86 (1.11-7.41)

0.02

Quintile 5

13 (18.8%)

25 (19%)

2.05 (0.78-5.40)

3.04 (1.15-7.99)

0.03

Prudent diet

     

Quintile 1

11 (16%)

26 (19.8%)

1

1

0.47

Quintile 2

13 (21.5%)

28 (21.4%)

0.95 (0.41-2.19)

1.02 (0.42-2.4)

0.95

Quintile 3

7 (12%)

30 (22.9%)

0.78 (0.32-1.87)

0.76 (0.31-1.92)

0.57

Quintile 4

9 (13%)

9 (7%)

1.68 (0.69-4.06)

1.39 (0.55-3.49)

0.48

Quintile 5

25 (36.2%)

33 (25.2%)

1.48 (0.73-2.99)

1.5 (0.71-3.18)

0.29

Depression

39 (56.5%)

81 (61.8%)

0 .85 (0.53-1.37)

0.91 (0.54-1.53)

0.17