Skip to main content

Table 3 Relative decrease in grey matter volumes in ALS patients compared to controls

From: Widespread sensorimotor and frontal cortical atrophy in Amyotrophic Lateral Sclerosis

Cluster

Side

Region

Brodmann's Area

MNI-Space

T-Value

P-Value

    

x

y

z

  

1

R

precentral gyrus

4

61

-6

20

7.29

0.011

 

R

precentral gyrus

6

60

2

28

5.85

0.032

 

R

precentral gyrus

6

60

-13

42

5.51

0.032

2

L

inferior parietal lobule

40

-51

-38

47

5.51

0.032

 

L

postcentral gyrus

3

-62

-18

33

4.93

0.032

 

L

postcentral gyrus

3

-58

-15

47

4.85

0.033

3

R

middle frontal gyrus

6

49

3

49

5.39

0.032

4

L

middle frontal gyrus

6

-46

0

43

5.09

0.032

5

R

postcentral gyrus

3

41

-25

46

5.03

0.032

6

R

postcentral gyrus

3

64

-23

41

5.01

0.032

 

R

inferior parietal lobule

40

44

-58

51

4.48

0.039

7

R

superior frontal gyrus

8

36

19

53

4.99

0.032

8

L

postcentral gyrus

1

52

-23

54

4.83

0.033

9

L

middle frontal gyrus

9

42

33

30

4.64

0.035

 

L

superior frontal gyrus

9

-36

36

38

4.21

0.048

10

R

superior frontal gyrus

8

9

34

57

4.55

0.037

  1. Coordinates (in mm) of peak group differences in MNI space (Montreal Neurological Institute, http://www.bic.mni.mcgill.ca) are given for information. Significant local maxima more than 8 mm apart were translated to brain anatomy by converting their coordinates from MNI space to Talairach space http://ric.uthscsa.edu/projects/talairachdaemon.html allowing for a search radius of 3 mm for nearest grey matter.