Widespread sensorimotor and frontal cortical atrophy in Amyotrophic Lateral Sclerosis

BMC Neurology

Table 1 Demographic information

patient #	age (yrs.)	sex	disease duration (mths.)	onset	ALSFRS-R at MRI	clinical diagnosis (EL Escorial)
1	59	m	30	limb	43	possible
2	59	m	13	limb	37	probable
3	31	m	17	limb	42	probable
4	68	m	22	bulbar	40	definite
5	65	m	25	limb	37	probable
6	66	f	41	limb	28	definite
7	53	m	38	limb	43	suspected
8	34	f	18	bulbar	39	probable
9	75	m	14	limb	44	suspected
10	62	m	18	bulbar	40	probable
11	49	m	19	limb	41	suspected
12	73	m	24	bulbar	33	definite
13	60	m	30	limb	33	probable
14	77	m	34	limb	33	probable
15	63	f	12	bulbar	45	probable
16	66	m	23	limb	48	suspected
17	72	m	25	bulbar	48	probable
mean ± S.D.	61 ± 13	f/m: 3/14	24 ± 09	b/l: 6/11	40 ± 06

Patients with suspected ALS were included in the study. All but one patient (#16) progressed to probable and definite ALS according to the El Escorial criteria on follow-up examination.
S.D. = standard deviation; f = female; m = male; b = bulbar; l = limb

ISSN: 1471-2377