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Table 2 Apo-1/Fas promoter polymorphism at position -670 in the enhancer region: Case-control analysis of genotype and alleles

From: An examination of the Apo-1/Fas promoter Mva I polymorphism in Japanese patients with multiple sclerosis

 

MS patients

Controls

 

Total

R-R

S-P

 
 

N = 114 (%)

N = 79 (%)

N = 35 (%)

N = 121 (%)

Genotype frequency

    

G/G

23 (20.2%)

16 (20.3%)

7 (20.0%)

25 (20.7%)

G/A

65 (57.0%)

44 (55.7%)

21 (60.0%)

63 (52.1%)

A/A

26 (22.8%)

19 (24.1%)

7 (20.0%)

33 (27.3%)

Allele frequency

    

G

111 (48.7%)

76 (48.1%)

35 (50.0%)

113 (46.7%)

A

117 (51.3%)

82 (51.9%)

35 (50.0%)

129 (53.3%)

  1. There was no significant difference in the distributions of -670 polymorphisms in Apo-1/Fas gene between MS patients and control subjects. Furthermore, there were no significant differences in the distributions of -670 polymorphisms in the Apo-1/Fas gene between patients with a relapsing-remitting course and those with a secondary-progressive course or between patients with either course and controls (P > 0.05).