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Table 1 Demographic and clinical characteristics of the subject groups (N = 52)

From: Evaluation of coexistence of Alzheimer’s disease in idiopathic normal pressure hydrocephalus using ELISA analyses for CSF biomarkers

 

iNPH

AD

Control

p1

p2

p3

n (M/F)

25 (12/13)

17 (10/7)

10 (3/7)

   

Age, yr

73.3 ± 7.0

72.2 ± 10.0

63.0 ± 6.7

0.924

0.029*

0.090

Education, yr

8.5 ± 5.2

6.1 ± 5.6

5.5 ± 5.2

0.469

0.498

0.970

K-MMSE

19.5 ± 6.9

18.3 ± 2.1

26.6 ± 2.5

0.832

0.042*

0.029*

Aβ42, pg/ml

579.8 ± 182.3

409.2 ± 166.1

691.8 ± 212.7

0.013*

0.241

0.001*

T-tau, pg/ml

131.9 ± 77.6

259.6 ± 161.5

196.9 ± 114.4

0.003*

0.312

0.382

P-tau, pg/ml

27.0 ± 9.6

51.3 ± 28.3

43.0 ± 28.5

0.002*

0.123

0.597

  1. Continuous variables are presented as mean ± standard deviation. iNPH: Idiopathic Normal Pressure Hydrocephalus; AD: Alzheimer’s Disease; M: Male; F: Female; K-MMSE: Korean version of Mini Mental Status Exam; p1: p-value between iNPH and AD; p2: p-value between iNPH and control; p3: p-value between AD and control.
  2. *p < 0.05.