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Table 4 Results of the univariate and multivariate Cox proportional hazard models for mortality

From: Clinical significance of cerebrovascular complications in patients with acute infective endocarditis: a retrospective analysis of a 12-year single-center experience

 

Univariate

Multivariate (model 1)

Multivariate (model 2)

Variables

HR (CI)

P

HR (CI)

P

HR (CI)

P

Age ≥65

2.730 (1.297-5.748)

0.008

3.386 (1.563-7.335)

0.002

3.138 (1.421-6.930)

0.005

Male

1.534 (0.745-3.159)

0.245

    

Diabetes mellitus

4.082 (1.975-8.435)

<0.001

    

Hypertension

2.805 (1.311-6.005)

0.008

    

Atrial fibrillation

2.152 (1.049-4.415)

0.037

    

History of CHF

2.773 (1.354-5.679)

0.005

    

Comorbidity index >2

6.002 (2.902-12.414)

<0.001

    

Prosthetic valves

3.076 (1.438-6.578)

0.004

  

2.819 (1.315-6.044)

0.008

Mitral valve IE

2.189 (0.764-6.274)

0.145

    

Aortic valve IE

0.719 (0.346-1.494)

0.377

    

Dual valve IE

1.280 (0.570-2.875)

0.550

    

Staphylococcus aureus

2.621 (1.166-5.891)

0.020

    

No surgery

3.936 (1.895-8.177)

<0.001

    

Major CVC

2.931 (1.304-6.586)

0.009

3.786 (1.635-8.771)

0.002

3.893 (1.649-9.194)

0.002

  1. HR, hazard ratio; CI, 95% confidence interval; IE, infective endocarditis; CVC, cerebrovascular complication.