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Figure 1 | BMC Neurology

Figure 1

From: Βeta-fibrinogen gene promoter A −455 allele associated with poor longterm survival among 55–71 years old Caucasian women in Finnish stroke cohort

Figure 1

The effect of FGB -455G/A genotype-by-smoking interaction on overall post stroke survival (all cause death endpoint) in the SAM cohort. Data shown on men (A: 55–71, and B: 72–85 years old); and women (C: 55–71, and D: 72–85 years old). Survival curves were obtained by Kaplan-Meyer log rank analysis that showed poorer longterm survival in the 55–71 year old women who carried the FBG -455G/A A-allele. This association was not dependent on smoking status in Cox regression forced model (non-smokers crude HR: 5.21, 95% CI 1.38-19.7; smokers crude HR: 7.03, 95% CI 1.81-27.3). There were no significant associations with Kaplan-Meyer (log rank) or Cox regression analysis between interaction terms and survival among men in both age groups or among older women (72–85 years).

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