Patient number | 1 | 2 | 3 | 4 |
---|---|---|---|---|
Psychiatric symptoms | - | + | - | - |
Cognitive deficits | + (working memory, attention, construction) | ++ | + | + |
(memory) | (memory) | (memory) | ||
Focal Seizures | + (dystonic faciobrachial) | + | + | + (dystonic faciobrachial) |
Anti-LGI1 IgG titer in serum | 1:100 | 1:100 | 1:100 | 1:100 |
Anti-LGI1 IgG titer in CSF | - | - | - | - |
CSF leukocytes/μl | 2 | 3 | 2 | 2 |
CSF oligoclonal bands | - | - | - | - |
MRI lesions | unspecific | bitemporal T2-hyperintensities | - | - |
Clinical onset to PET and treatment in months | 6 | 1 | 12 | 2 |
mRS at time of PET | 2 | 2 | 2 | 2 |
PET in narcosis | - | - | - | - |
Evidence of Tumor | - | - | - | - |
Intensive care treatment | - | - | - | - |
Methylprednisolone | + | + | + | + |
Plasmapheresis | + (3 months interval) | + | + | - |
Immunoglobulins | - | - | + | + |
Immunosuppressive therapy | - | - | Cyclophospha-mide | - |
mRS at follow up (months after PET) | 1 | 0 | 3 | 0 |
(31) | (24) | (9) | (18) |