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Table 5 Ordinal logistic regression analyses according to the location of CMBs

From: Cystatin C, a novel indicator of renal function, reflects severity of cerebral microbleeds

Variables

N

Unadjusted OR

95% CI

P

Adjusted OR

95% CI

P

Strictly lobar CMBs

54

      

 Quartiles of cystatin C

       

 Q4(≥66.7)

23

6.14

0.01-1.78

0.13

5.23

0.30-8.98

0.13

 Q3(54.7-66.7)

14

4.84

0.01-3.80

0.29

2.82

0.46-1.69

0.11

 Q2(47.2-54.7)

5

1.54

0.03-11.2

0.76

1.37

0.05-3.77

0.85

 Q1(≤47.2), ref

12

      

 p for trend

   

0.10

  

0.50

Deep or infratentorial CMBs

135

      

 Quartiles of cystatin C

       

 Q4(≥66.7)

45

5.00

1.30-1.91

0.02

6.27

1.48-2.64

0.01

 Q3(54.7-66.7)

39

1.50

0.51-4.34

0.46

2.48

0.76-8.02

0.13

 Q2(47.2-54.7)

23

1.00

0.40-2.28

0.93

1.10

0.43-2.78

0.83

 Q1(≤47.2),ref

28

      

 p for trend

   

0.02

  

0.02

  1. Adjusted for the covariates: age, sex, total cholesterol, diabetes, hypertension, dyslipidemia, previous heart disease, smoking, previous anti thrombotic or anticoagulant use and white matter lesions.