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Table 1 Anti-NMDA-R follow-up of the titration in CSF and in serum (qualitative and quantitative)

From: Extensive myelitis associated with anti-NMDA receptor antibodies

Date

Jun 23rd

Jul 2nd

Jul 10th

Jul 11th

Jul 14th

Jul 16th

Jul 17th

Jul 23rd

Jul 30th

Aug 6th

Aug 13th

Oct 17th

CSF

+ (1/10)

+ (low)

NA

NA

NA

NA

-

NA

NA

NA

NA

-

Anti-NMDA-R in serum

NA

NA

+ (1/10)

+ (1/10)

-

+ (low)

-

-

+ (low)

NA

+ (1/10)

-

Methylprednisolone (1 g/day IV)

3 days

 

5 days

         

PLEX

  

Yes

Yes

Yes

Yes

Yes

     

Rituximab (375 mg/m2/week during 4 weeks)

       

Yes

Yes

Yes

Yes

 
  1. Jun, June; Jul, July; Aug, August; Oct, October; CSF, cerebrospinal fluid; NA, not available; PLEX, plasma exchange; 5 PLEX were performed followed by infusions of rituximab (375 mg/m2/week during 4 weeks).