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Table 2 The proportions of clinical radiological variables by the severity of obesity

From: Paradoxical effect of obesity on hemorrhagic transformation after acute ischemic stroke

 

Underweight

Normal weight

Overweight

Obesity I

Obesity II

Pfor trend*

 

(< 18.5 kg/m2)

(18.5-22.9 kg/m2)

(23.0-24.9 kg/m2)

(25.0-29.9 kg/m2)

(≥ 30 kg/m2)

 

Variables (n = 365)

n = 18 (4.9%)

n = 107 (29.3%)

n = 94 (25.8%)

n = 134 (36.7%)

n = 12 (3.3%)

 

Demographic

      

  Age, y

71.1 ± 11.2

65.3 ± 12.7

65.2 ± 11.8

63.4 ± 11.1

61.0 ± 12.8

0.08

  Gender, male

15 (83.3%)

73 (68.2%)

62 (66.0%)

88 (65.7%)

8 (66.7%)

0.67

Clinical

      

  Hypertension†

7 (38.9%)

50 (46.7%)

58 (61.7%)

96 (71.6%)

8 (66.7%)

< 0.01

  Diabetes

3 (16.7%)

29 (27.1%)

32 (34.0%)

44 (32.8%)

2 (16.7%)

0.38

  Hyperlipidemia

1 (5.6%)

13 (12.1%)

17 (18.1%)

20 (14.9%)

1 (8.3%)

0.55

  Current smoking

7 (38.9%)

21 (19.6%)

23 (24.5%)

23 (17.2%)

2 (16.7%)

0.23

  Initial NIHSS score†

5 (3–12)

5 (2–11)

4 (2–9)

3 (2–5)

3 (1–6)

< 0.01

  Thrombolysis

0 (0%)

9 (8.4%)

6 (6.4%)

9 (6.7%)

0 (0%)

0.61

  Acute heparin treatment

9 (50%)

37 (34.6%)

31 (33%)

39 (29.1%)

3 (25%)

0.44

  Antiplatelet Use

0

5 (4.7%)

4 (4.3%)

2 (1.5%)

0

0.48

  Warfarin Use

0

2 (1.9%)

5 (5.3%)

4 (3.0%)

0

0.54

Radiological

      

  Hemorrhagic transformation†

4 (22.2%)

26 (24.3%)

14 (14.9%)

14 (10.4%)

1 (8.3%)

0.04

  Advanced WMLs

6 (35.3%)

26 (25%)

24 (26.1%)

35 (26.3%)

1 (8.3%)

0.6

  Presence of microbleeds

2 (11.8%)

20 (19.4%)

21 (22.8%)

36 (27.1%)

4 (33.3%)

0.42

  1. Values are mean ± SD, median (interquartile range), or number of participants (percentage).
  2. NIHSS indicates National Institute of Health Stroke Scale; WMLs, white matter lesion.
  3. *Based on χ2 test of trend across the severity of obesity.
  4. P < 0.05.