From: Paradoxical effect of obesity on hemorrhagic transformation after acute ischemic stroke
Underweight | Normal weight | Overweight | Obesity I | Obesity II | Pfor trend* | |
---|---|---|---|---|---|---|
(< 18.5 kg/m2) | (18.5-22.9 kg/m2) | (23.0-24.9 kg/m2) | (25.0-29.9 kg/m2) | (≥ 30 kg/m2) | ||
Variables (n = 365) | n = 18 (4.9%) | n = 107 (29.3%) | n = 94 (25.8%) | n = 134 (36.7%) | n = 12 (3.3%) | |
Demographic | ||||||
Age, y | 71.1 ± 11.2 | 65.3 ± 12.7 | 65.2 ± 11.8 | 63.4 ± 11.1 | 61.0 ± 12.8 | 0.08 |
Gender, male | 15 (83.3%) | 73 (68.2%) | 62 (66.0%) | 88 (65.7%) | 8 (66.7%) | 0.67 |
Clinical | ||||||
Hypertension† | 7 (38.9%) | 50 (46.7%) | 58 (61.7%) | 96 (71.6%) | 8 (66.7%) | < 0.01 |
Diabetes | 3 (16.7%) | 29 (27.1%) | 32 (34.0%) | 44 (32.8%) | 2 (16.7%) | 0.38 |
Hyperlipidemia | 1 (5.6%) | 13 (12.1%) | 17 (18.1%) | 20 (14.9%) | 1 (8.3%) | 0.55 |
Current smoking | 7 (38.9%) | 21 (19.6%) | 23 (24.5%) | 23 (17.2%) | 2 (16.7%) | 0.23 |
Initial NIHSS score† | 5 (3–12) | 5 (2–11) | 4 (2–9) | 3 (2–5) | 3 (1–6) | < 0.01 |
Thrombolysis | 0 (0%) | 9 (8.4%) | 6 (6.4%) | 9 (6.7%) | 0 (0%) | 0.61 |
Acute heparin treatment | 9 (50%) | 37 (34.6%) | 31 (33%) | 39 (29.1%) | 3 (25%) | 0.44 |
Antiplatelet Use | 0 | 5 (4.7%) | 4 (4.3%) | 2 (1.5%) | 0 | 0.48 |
Warfarin Use | 0 | 2 (1.9%) | 5 (5.3%) | 4 (3.0%) | 0 | 0.54 |
Radiological | ||||||
Hemorrhagic transformation† | 4 (22.2%) | 26 (24.3%) | 14 (14.9%) | 14 (10.4%) | 1 (8.3%) | 0.04 |
Advanced WMLs | 6 (35.3%) | 26 (25%) | 24 (26.1%) | 35 (26.3%) | 1 (8.3%) | 0.6 |
Presence of microbleeds | 2 (11.8%) | 20 (19.4%) | 21 (22.8%) | 36 (27.1%) | 4 (33.3%) | 0.42 |