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Table 2 Relationship between selected parameters and cTNI elevation in patients with epileptic seizure

From: Cardiac Troponin I elevation after epileptic seizure

 

Total cohort (n = 741)

cTNI elevation(n = 50)

cTNI negative(n = 691)

P*

P

Age (years); median (range)

47.8 (17.5 –89.9)

61.9 (21.6 – 88.1)

46.8 (17.5 – 89.9)

<0.001

0.07

Gender

   

0.77

 

 Female

303 (40.9%)

19 (38%)

284 (41.1%)

  

 Male

438 (59.1%)

31 (62%)

407 (58.9%)

  

CK elevated on admission

303 (40.9%)

27(54%)

276 (39.9%)

<0.001

0.002

Further subsequent CK increase after admission

187 (25.2%)

24 (48%)

163 (23.6%)

<0.001

 

Cr elevated on admission

85 (11.5%)

16 (32%)

69 (10%)

0.05

0.14

eGFR (ml/min/1,73 m2 body surface), median (range)

76.9 (43.8 – 162.8)

76.1 (45.9 – 162.8)

76.9 (43.8 – 159.3)

0.40

 

Hypertension

155 (20.9%)

16 (32%)

139 (20.1%)

0.07

 

Hypercholesterolemia

117 (15.8%)

12 (24%)

105 (15.2%)

0.11

 

Diabetes

75 (10.1%)

9 (12%)

66 (9.6%)

0.08

 

Intake of Beta-blocker

92(12.4%)

15(30%)

77 (11.1%)

<0.001

0.63

Known CAD

96 (13%)

18 (36%)

78 (11.3%)

<0.001

0.56

Vascular risk profile

193 (33.9%)

32(64%)

161(23.3%)

<0.001

0.001

Regular alcohol consumption

222 (30%)

17 (34%)

205 (29.7%)

0.52

 

Known epilepsy

251 (33.9%)

25 (50%)

226 (32.7%)

0.02

0.18

Symptomatic epilepsy

249 (33.6%)

23 (46%)

226 (32.7%)

0.06

0.52

Intake anticonvulsants

231 (31.2%)

23 (46%)

208 (30.1%)

0.02

0.34

  1. *P value calculated in the univariate analysis.
  2. P value calculated in the logistical regression.
  3. CK refers to serum creatine kinase.
  4. Cr refers to serum creatinine.
  5. CK cut-off level > 140U/l in females and > 174 U/l in males.
  6. Cr cut-off level > 1.2 mg/dl in females and > 1.3 mg/dl in males.
  7. eGFR refers to estimated glomerular filtration rate.