Evaluating the cost effectiveness of donepezil in the treatment of Alzheimer's disease in Germany using discrete event simulation

Table 3 Cost inputs

Care costs by disease severity (MMSE)		Monthly costs	Source
Mild	≥ 25	€184	Adapted from Teipel et al. 2007[18]
	≥ 20 - < 25	€593
Moderate	≥ 15 - < 20	€1,275
	≥ 10 - < 15	€1,958
Severe	< 10	€2,981
Drugs		Treatment costs per day**	Source
Donepezil 10 mg		€4.20	Rote Liste^® 2008[49]
Memantine 20 mg		€3.83	Rote Liste^® 2008[49]
Outpatient treatment monitoring		Costs per quarter	Source
GP visit, geriatric assessment, MMSE test (one per quarter)		€53.47*	EBM2008[46]

* Including once-quarterly lump-sum for GP visit (€37.74), geriatric assessment (€ 13.69) and MMSE test (€2.04)
** Treatment costs per day are calculated based on the N3 package price provided in the Rote Liste^® converted to a daily cost based on the number of tablets per pack

ISSN: 1471-2377