Table 2 Retinal nerve fibre layer (RNFL) thickness in different sectors
From: Retinal nerve fibre layer loss in hereditary spastic paraplegias is restricted to complex phenotypes
Global (μm) | Temporal (μm) | Temporal superior (μm) | Nasal superior (μm) | Nasal (μm) | Nasal inferior (μm) | Temporal inferior (μm) | Foveal (μm) | |
|---|---|---|---|---|---|---|---|---|
Controls (n=28) | 99.82±7.41 | 76.50±9.18 | 136.86±12.32 | 103.36±18.89 | 75.18±12.21 | 109.50±19.86 | 145.39±11.82 | 230.21±13.64 |
HSP-a (n=28) | 98.57±10.67 p=0.61 | 71.86±14.23 p=0.15 | 138.39±17.19 p=0.70 | 104.71±16.74 p=0.77 | 75±14.16 p=0.96 | 107.57±19.27 p=0.71 | 143.54±20.23 p=0.68 | 223.61±15.5 p=0.1 |
HSP-p (n=22) | 100.82±9.76 p=0.88 | 76.09±10.48 p=0.69 | 139.59±17.31 p=0.88 | 104.82±16.43 p=0.91 | 76.18±14.91 p=0.92 | 110.45±19.47 p=1 | 146.36±20.27 p=0.91 | 221.23±15.28 p*<0.05 |
HSP-c (n=6) | 90.33±10.58 p=0.06 | 56.33±16.24 p*<0.05 | 134±17.58 p=0.66 | 104.33±19.48 p=0.82 | 70.67±10.93 p=0.92 | 97±15.54 p=0.68 | 133.17±17.88 p*<0.05 | 232.33±14.15 p=0.08 |
SPG4 (n=13) | 103.77±10.43 p=0.98 | 77.31±11.53 p=0.57 | 141.23±18.19 p=1 | 108.92±18.55 p=0.91 | 78.77±15.33 p=0.91 | 115.69±22.29 p=0.54 | 151.92±21.98 p=0.83 | 219.01±13.31 p*<0.05 |
SPG5 (n=1) | 98 p=n.a. | 81 p=n.a. | 139 p=n.a. | 86 p=n.a. | 72 p=n.a. | 107 p=n.a. | 143 p=n.a. | 209 p=n.a. |
SPG7 (n=3) | 88.67±18.45 p=0.48 | 51.33±27.43 p=0.13 | 141±23.9 p=0.69 | 92.33±19.86 p=0.81 | 77±17.45 p=0.26 | 92.67±7.09 p=0.78 | 124.33±21.22 p=0.10 | 222±12.77 p=0.14 |