| Cohort 1 | Cohort 2 | |||||
---|---|---|---|---|---|---|---|
 | HC | CFS | HC | All CFS | CFS+MO | CFS+MA | CFS+T |
Headache Severity Score | 0.85 [0.69-1.01] N = 191 | 2.64 [2.45-2.83] n = 152 p < 10-10 * | 0.55 [0.11-0.99] n = 20 | 2.63 [2.33-2.93] n = 63 p < 10-9 ** | 2.76 [2.39-3.13] n = 38 p < 10-8 ** | 2.93 [2.43-3.43] n = 14 p = 10-6 ** | 1.82 [1.08-2.56] n = 11 p = 0.03 ** |
McGill Sensory Score | 6.5 [5.2-8.8] n = 109 | 8.8 [7.0-10.5] n = 55 p = 0.002 * | 4.3 [0.9-7.7] n = 18 | 13.9 [11.5-16.3] n = 44 p = 0.0004** | 13.6 [10.5-16.6] n = 24 p = 0.002** | 17.5 [11.6-23.4] n = 12 p = 0.002 ** | 9.50 [7.0-12.0] n = 8 |
Neuro-Construct | 2.39 [1.58-3.20] n = 57 | 7.00 [4.91-9.01] n = 21 p = 0.000005* | 1.71 [0.36-3.06] n = 17 | 7.08 [5.93-8.23] n = 48 p = 0.00003** | 6.33 [4.92-7.74] n = 30 p = 0.0007** p = 0.002*** | 11.4 [10.3-12.5] n = 10 p = 10-8 ** | 4.50 [2.84-6.16] n = 8 p = 0.00002*** |
Cardio-Construct | 1.46 [0.79-2.13] n = 57 | 2.86 [1.45-4.27] n = 21 p = 0.053 | 0.76 [-0.07-1.59] n = 17 | 3.22 [2.30-4.14] n = 45 p = 0.02** | 2.70 [1.67-3.73] n = 27 p = 0.045*** | 5.90 [3.55-8.25] n = 10 p = 0.0004 ** | 1.63 [0.65-2.61] n = 8 p = 0.049 *** |