Table 3 Final model for the stepwise Cox hazard model analysis showing Hazard Ratio (with relative confidence intervals and p-values) for worsening in disability after the increase of IFNB dose.
| Â | HR | 95% C.I. | p-value |
|---|---|---|---|
Male gender | 1.68 | 0.88 - 2.13 | 0.1 |
Age at switch (each year) | 0.98 | 0.94 - 1-02 | 0.3 |
Interaction term (relapse * active MRI scan at switch) | 2.14 | 1.16 - 3.96 | 0.01 |
EDSS score at switch (each point) | 1.77 | 1.39 - 2.26 | < 0.001 |
IFNB type (Betaferon or Rebif 44) | 0.83 | 0.28 - 2.85 | 0.7 |