Cognitive function and quality of life in multiple sclerosis patients: a cross-sectional study

BMC Neurology

Table 1 Clinical characteristics, self-reported quality of life and cognitive functions

		N = 124
Disease duration in years	median [range]	9.86 [0-31.00]
EDSS^a	median [range]	4.75 [1.00-8.00]
Depression	BDI^b (0-39)	10.42 ± 5.77
	BDI^b classes (moderate/severe depression)	47 (70.1%)
Fatigue	MFIS^c Physical (0-36)	25.97 ± 7.27
	MFIS^c Cognitive (0-40)	18.75 ± 8.87
	MFIS^c Psychosocial (0-8)	5.35 ± 2.07
	MFIS^c Total (0-84)	50.03 ± 15.31
SF36^d	Physical function (0-100)	33.88 ± 26.78
	Social functioning (0-100)	50.88 ± 23.09
	Role physical (0-100)	20.95 ± 30.62
	Role emotional (0-100)	32.28 ± 38.16
	Mental health (0-100)	49.90 ± 17.81
	Vitality (0-100)	32.48 ± 19.12
	Body pain (0-100)	45.80 ± 26.21
	General health (0-100)	39.72 ± 20.28
	Mental composite score	32.64 ± 8.83
	Physical composite score	38.59 ± 9.53
MusiQoL^e	Activity of daily living (0-100)	29.94 ± 21.24
	Psychological well-being (0-100)	50.97 ± 24.79
	Relationships with friends (0-100)	62.03 ± 24.21
	Symptoms (0-100)	54.31 ± 23.85
	Relationships with family (0-100)	72.17 ± 24.89
	Relationships with health care system (0-100)	69.49 ± 19.48
	Sentimental and sexual life (0-100)	49.19 ± 31.75
	Coping (0-100)	55.64 ± 29.40
	Rejection (0-100)	66.00 ± 33.42
	Index (0-100)	56.63 ± 12.57
BRB-N subtests^f	SRT-L^g	46.44 ± 15.27
	SRT-C^g	40.17 ± 15.72
	SRT-D^g	9.37 ± 2.96
	SPART-T^g	16.40 ± 5.20
	SPART-D^g	5.29 ± 2.36
	SDMT^g	35.68 ± 11.92
	PASAT-3^g	34.15 ± 15.02
	WLG^g	25.32 ± 8.40

^aEDSS Expanded Disability Status Scale; the higher the score, the more severe the disability
^bBDI Beck Depression Inventory; the higher the score, the worse the depression
^cMFIS Modified Fatigue Impact Scale; the higher the score, the more severe the fatigue
^dSF36 Short Form 36; the higher the score, the higher the QoL level
^eMusiQoL Multiple Sclerosis International Quality of Life; the higher the score, the higher the QoL level
^fBRB-N subtests; the higher the score, the higher the cognitive performance
^gSRT-L Selective Reminding Test Long-term, SRT-C Selective Reminding Test Consistent long-term, SRT-D Selective Reminding Test Delayed, SPART-T SPAtial Recall Test Total, SPART-D SPAtial Recall Test Delayed, SDMT Symbol Digit Modalities Test, PASAT-3 Paced Auditory Serial Addition Test 3 s, WLG Word List Generation test

ISSN: 1471-2377