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Table 2 Demographic characteristics of survival and non-survival groups during follow-up

From: Clinical characteristics and favorable long-term outcomes for patients with idiopathic inflammatory myopathies: a retrospective single center study in China

Variables

Non-survival group

Survival group

P values

No. of patients (%)

32(17.0)

156(83.0)

 

Sex, no. (%)

   

   Male: female ratio

01:01.9

01:02.1

0.837

Classification of diagnosis

   

   PM

5(15.6)

37(23.7)

0.363

   DM

20(62.5)

80(51.3)

0.331

   ADM

4(12.5)

9(5.8)

0.241

   OM

2(6.25)

24(15.4)

0.261

   JM

1(3.13)

6(3.9)

1

Mean age ± S.D at onset (year)

52.9 ± 15.8

41.9 ± 15.2

0

Disease duration from onset to diagnosis, median (IQR) year

3.8(2, 12.8)

6.5(3, 12)

0.215

Skin ulcers, (%)

6(18.8)

15(9.6)

0.212

Complicated with ILD at disease course, (%)

17(53.1)

75(48.1)

0.558

Complicated with PAH at disease course, (%)

3(9.4)

17(10.9)

1

Complicated with malignancy, (%)e

7(21.9)

4(2.6)

0

Complicated with dysphagia at disease course, (%)

8(25.0)

67(42.9)

0.074

Cardiac involvement at disease course, (%)

17(53.1)

47(30.1)

0.023

Raynaud phenomenon at disease course, (%)

4(12.5)

25(16.0)

0.79

Low TP level† at diagnosis, (%)

10(31.3)

24(2.6)

0.044

Low ALB levels† at diagnosis, (%)

16(50.0)

46(29.5)

0.038

Elevated IgG†† at diagnosis, (%)

8(25)

47(30.1)

0.672

Elevated IgA†† at diagnosis, (%)

9(28.1)

25(15.4)

0.122

Elevated IgM†† at diagnosis, (%)

5(15.6)

20(12.8)

0.775

Creatine kinase at initial visit in our center, median (IQR)

260.5

(71.8, 1173.8)

491.5

(83.3, 1613.5)

0.489

Autoantibodies positive at disease course, (%)

   

   ANA positive

16(50.0)

85(54.5)

0.699

   Anti-RNP positive

4(12.5)

13(8.3)

0.497

   Anti-Jo-1 positive

0(0.0)

24(15.4)

0.016

   Anti-SSA positive

2(6.3)

33(21.2)

0.048

MYOACT global disease activity, 10-cm VAS score at disease onset

6.21 ± 2.61

6.64 ± 2.60

0.408

MYOACT muscle disease activity, 10-cm VAS score at disease onset

7.09 ± 1.34

6.91 ± 1.3

0.47

MYOACT, subscale VAS score > 0 at disease onset

   

   Constitutional

25(78.1)

129(82.7)

0.614

   Cutaneous

25(78.1)

111(71.2)

0.518

   Skeletal

10(31.3)

42(26.9)

0.666

   Gastrointestinal

9(28.1)

57(36.5)

0.421

   Pulmonary

4(12.5)

12(7.7)

0.483

   Cardiac

9(28.1)

35(22.4)

0.497

  1. †refers to values that are below the lower limit of normal laboratory assay standards.
  2. ††refers to values that are higher than the upper limit of normal laboratory assay.
  3. ANA, antinuclear antibody; RNP, ribonucleoprotein; SSA: Sjögren's syndrome antigen.