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Table 3 ROC analysis of the measured parameters showing area under the curve,cutoff values, sensitivity and specificity.

From: Novel metabolic biomarkers related to sulfur-dependent detoxification pathways in autistic patients of Saudi Arabia

Parameter

Area under the curve

Cutoff value

Sensitivity %

Specificity %

Total glutathione

1.000

9.320

100.0%

20.0%

Oxidised glutathione (GSSG)

0.919

0.380

80.0%

80.0%

GSH/GSSG

1.000

31.100

100.0%

20.0%

Glutathione reductase

0.650

75.620

30.0%

90.0%

Glutathione- S- transferase

0.803

1.100

100.0%

15.0%

Peroxiredoxin 1

0.915

26.240

90.0%

80.0%

Peroxiredoxin 3

1.000

26.990

100.0%

85.0%

Thioredoxin 1

0.993

52.140

100.0%

85.0%

Thioredoxin reductase

0.881

2.350

65.0%

85.0%