High degree of efficacy in the treatment of cyclic vomiting syndrome with combined co-enzyme Q10, L-carnitine and amitriptyline, a case series

Table 2 Response to treatment in 30 cases with cyclic vomiting syndrome

Amitriptyline	Cyproheptadine	Coenzyme Q10	L-carnitine	Outcome: Episodes Resolved	Outcome: Episodes > 75% Improvement	Outcome: Episodes > 50% Improvement	Outcome: Treatment Failure
		+	+	3	3^a
+				1			1 ^b
+		+		3 ^c
+			+	2 ^d
+		+	+	10		1 ^b	2 ^b
	+			1
	+	+		1
	+		+	1
	+	+	+	1

^a All 3 families elected not to treat with amitriptyline despite symptoms
^bSee text
^cIn one of those cases, amitriptyline was not tolerated, yet episodes resolved on topiramate + co-enzyme Q10
^dIn one of those cases, episodes returned years later, then resolved on topiramate, while still on carnitine.

ISSN: 1471-2377