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Figure 9 | BMC Neurology

Figure 9

From: Identification of a novel biomarker candidate, a 4.8-kDa peptide fragment from a neurosecretory protein VGF precursor, by proteomic analysis of cerebrospinal fluid from children with acute encephalopathy using SELDI-TOF-MS

Figure 9

Peptide Mass Fingerprint (PMF) analysis of the purified 4.8-kDa protein. PMF analysis was used to distinguish between the two protein candidates identified by MS/MS. Spectrum data and sequences were obtained from the peptides digested by trypsin. The MS of the tryptic digest contained an m/z 4280 peak as predicted from the neurosecretory protein VGF precursor [Homo sapiens] sequence, and no m/z 4337 peak as predicted from the neuro-endocrine specific protein VGF [Homo sapiens] sequence.

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